Shing Hwa Liu Selected Research

honokiol

5/2016	Preclinical effects of honokiol on treating glioblastoma multiforme via G1 phase arrest and cell apoptosis.
4/2014	Honokiol, a low molecular weight natural product, prevents inflammatory response and cartilage matrix degradation in human osteoarthritis chondrocytes.
5/2012	Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis.
1/2012	Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice.
3/2011	Honokiol rescues sepsis-associated acute lung injury and lethality via the inhibition of oxidative stress and inflammation.
8/2010	Honokiol inhibits gastric tumourigenesis by activation of 15-lipoxygenase-1 and consequent inhibition of peroxisome proliferator-activated receptor-gamma and COX-2-dependent signals.
6/2008	Inhibition of NADPH oxidase-related oxidative stress-triggered signaling by honokiol suppresses high glucose-induced human endothelial cell apoptosis.
10/2007	Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Shing Hwa Liu Research Topics

Disease

7	Hyperglycemia 01/2015 - 07/2004
6	Neoplasms (Cancer) 05/2016 - 05/2004
5	Inflammation (Inflammations) 04/2014 - 08/2005
3	Acute Lung Injury 05/2012 - 06/2004
3	Stomach Neoplasms (Stomach Cancer) 01/2012 - 10/2007
3	Glucose Intolerance 02/2011 - 06/2006
2	Hypoxia (Hypoxemia) 05/2016 - 11/2015
2	Osteoarthritis 04/2014 - 01/2013
2	Lung Injury 05/2012 - 06/2004
2	Diabetes Mellitus 09/2011 - 11/2009
2	Endotoxemia 03/2011 - 06/2004
2	Edema (Dropsy) 03/2011 - 06/2004
2	Type 2 Diabetes Mellitus (MODY) 02/2011 - 06/2009
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2008 - 01/2008
1	Atherosclerosis 01/2017
1	Glioma (Gliomas) 05/2016
1	Neuroblastoma 05/2016
1	Glioblastoma (Glioblastoma Multiforme) 05/2016
1	Squamous Cell Carcinoma of Head and Neck 01/2016
1	Blister (Bulla) 01/2016
1	Breast Neoplasms (Breast Cancer) 01/2016
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2016
1	Protein Deficiency 11/2015
1	Reperfusion Injury 11/2015
1	Vascular System Injuries 06/2013
1	Necrosis 01/2013
1	Pancreatitis 05/2012
1	Carcinogenesis 01/2012
1	Neoplasm Metastasis (Metastasis) 01/2012
1	Ototoxicity 09/2011
1	Bone Resorption 06/2011
1	Septic Shock (Toxic Shock Syndrome) 03/2011
1	Sepsis (Septicemia) 03/2011
1	Urologic Diseases (Urinary Tract Disease) 08/2009

Drug/Important Bio-Agent (IBA)

8	honokiolIBA 05/2016 - 10/2007
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2012 - 06/2004
4	Biological ProductsIBA 04/2014 - 11/2009
4	Proteins (Proteins, Gene)FDA Link 05/2012 - 06/2004
3	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2016 - 09/2011
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2016 - 07/2004
3	Advanced Glycation End ProductsIBA 01/2015 - 01/2013
3	Insulin (Novolin)FDA Link 06/2009 - 06/2006
2	Benzo(a)pyreneIBA 01/2017 - 05/2004
2	Catechin (Z 7300)IBA 05/2016 - 02/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2012 - 03/2011
2	LipopolysaccharidesIBA 05/2012 - 06/2004
2	Caspase 3 (Caspase-3)IBA 05/2012 - 06/2008
2	CalpainIBA 01/2012 - 10/2007
2	PPAR gammaIBA 08/2010 - 09/2007
2	Streptozocin (Streptozotocin)FDA Link 01/2008 - 09/2007
2	Phosphatidylinositols (Phosphatidylinositol)IBA 09/2007 - 08/2005
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 08/2005 - 07/2004
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2017
1	Sirolimus (Rapamycin)FDA Link 05/2016
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 05/2016
1	TeaIBA 05/2016
1	Cyclin D1IBA 05/2016
1	PolyphenolsIBA 05/2016
1	CaspasesIBA 05/2016
1	DisintegrinsIBA 01/2016
1	TensinsIBA 01/2016
1	Cantharidin (Cantharides)IBA 01/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2016
1	Metalloproteases (Metalloproteinases)IBA 01/2016
1	Therapeutic UsesIBA 01/2016
1	MicroRNAs (MicroRNA)IBA 01/2016
1	Cadherins (E-Cadherin)IBA 01/2016
1	fucoidanIBA 01/2016
1	CCAAT-Enhancer-Binding ProteinsIBA 11/2015
1	CytokinesIBA 04/2014
1	N(6)-carboxymethyllysine (carboxymethyllysine)IBA 06/2013
1	CollagenIBA 01/2013
1	Diatrizoate Meglumine (Gastrograffin)FDA LinkGeneric 01/2013
1	CeruletideIBA 05/2012
1	Lipase (Acid Lipase)FDA Link 05/2012
1	Interleukin-1 (Interleukin 1)IBA 05/2012
1	Amylases FDA Link 05/2012
1	Tyrosine (L-Tyrosine)FDA Link 01/2012
1	DNA (Deoxyribonucleic Acid)IBA 01/2012
1	ArsenicIBA 09/2011
1	Gentamicins (Gentamicin)FDA LinkGeneric 09/2011
1	Drinking WaterIBA 09/2011
1	Ginkgo biloba extract (Rokan)IBA 09/2011
1	Cisplatin (Platino)FDA LinkGeneric 08/2011
1	Alkaline PhosphataseIBA 06/2011
1	Caffeine (No Doz)FDA LinkGeneric 06/2011
1	HMGB ProteinsIBA 03/2011
1	Nitric Oxide Synthase (NO Synthase)IBA 03/2011
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2011
1	Insulin SecretagoguesIBA 02/2011
1	Heavy MetalsIBA 11/2009
1	Interleukin-6 (Interleukin 6)IBA 08/2009
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2009

Therapy/Procedure

2	Therapeutics 05/2016 - 01/2012
2	Heterologous Transplantation (Xenotransplantation) 01/2008 - 01/2008
1	Injections 05/2012
1	Intraperitoneal Injections 05/2012
1	Critical Care (Surgical Intensive Care) 03/2011
1	Ligation 03/2011
1	Punctures 03/2011